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Find out more on how to host your own Frontiers Research Topic or contribute to one as an author. Research Topic Molecular and structural roles of carbohydrates and glycoproteins in pathogen invasion and host innate immunity. Submission closed. Overview Articles Authors Impact. About this Research Topic Carbohydrates and glycoproteins play central roles in cellular invasion or infection by pathogens and the innate arm of the host immune system.
Cerami A. Tokunaga T. Yamamoto S. Akagawa K. Landy M. Koszinowski U. Kramer M. Yednock T. Stoolman L. Rosen S. Butcher E. Cell Boil. Rosen G. Singer M. Springer G. Allergy , 15 , 9 — Hortin R. Galili U. Mandrell R. Hamadeh R. Shohet S. Griffis J. Etienne-Decerf J. Malaise M. Mahieu P. Winand R. A marker of progression in autoimmune thyroid disorders and endocrine ophthalmopathy Acta. Flechner I.
Knyszynski A. Danon D. Rachmilewitz E. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Sign In. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume 1. This article was originally published in.
Article Contents Abstract. Carbohydrates as recognition molecules in infection and immunity. Correspondence to: D. Oxford Academic. Cite Cite D. Select Format Select format. Permissions Icon Permissions. Abstract Consideration of host-parasite interactions encompasses a wide range of phenomena from adhesion to epithelial surfaces to interactions with cells of the immune system.
Carbohydrates, Recognition , Macrophages , Bacterium , Blood group antigens. Google Scholar Crossref. Search ADS. The characteristics of binding of Corynebacterium parvum to glass-adherent mouse peritoneal exudate cells. The role of cell wall carbohydrates in binding of microorganisms to mouse peritoneal exudate macrophages. Google Scholar PubMed.
Adherence of Escherichia coli to human mucosal cells mediated by mannose receptors. Bacterial Adherence: Adhesin-receptor interactions mediating the attachment of bacteria to mucosal surfaces. Surface sugars of animal cells as determinants of recognition in bacterial adherence.
Fine dissection of binding epitopes on carbohydrate receptors for microbiological ligands. Structural model for Neisseria gonorrhoeae pili and identification of a non-pilin-mediated glycolipid binding activity. Inhibition of the interaction between fimbrial haemagglutinins and erythrocytes by D-mannose and other carbohydrates. Haemagglutination properties and adherence ability of Aeromonas hydrophilia. Sugar inhibition of oral Fusobacterium nucleatum haemagglutination and cell binding.
Mannose-binding activity of Escherichia coli: a determinant of attachment and ingestion of the bacteria by macrophages. Structure studies on the myxovirus haemagglutination inhibitor of human erythrocytes. Ia antigenic specificities are oligosaccharide in nature: hapten inhibition studies. Glycoprotein antigens of the lymphocyte surface and their purification by antibody affinity chromatography. Monoclonal anti-Fc receptor IgG blocks antibody enhancement of viral replication in macrophages.
Is allograft rejection a clue to the mechanism promoting MHC polymorphism. Antigens common to human and bacterial cells. IV Studies of human pneumoccocal disease. Virulence of Escherichia coli in experimental hematogenous pyelonephritis in mice. Inhibition of blood clearance and hepatic tissue binding of Escherichia coli by liver lectin-specific sugars and glycoproteins. Liver cell and macrophage surface lectins as determinants of recognition in blood clearance and cellular attachment of bacteria.
Demonstration of carbohydrate and protein determined Ia antigens by monoclonal antibodies. Carbohydrate-mediated clearance of antibody antigen complexes from the circulation. A heterophile carbohydrate moiety common to mammalian IgM and erythrocytes detected by chicken IgM antibody. Evidence for receptor mediated binding of glycoproteins, glycoconjugates and lysosomal glycosidases by alveolar macrophages.
Presence of a lectin-like receptor for D-galactose on rat peritoneal macrophages. Receptor mediated pinocytosis of mannose glycoconjugates by macrophages: characterization and evidence for receptor recycling. Yeast mannans inhibit binding and phagocytosis of zymosan by mouse peritoneal macrophages. Expression of a mannose fucosyl receptor for endocytosis on cultured macrophages and their hybrids. Plasma membrane markers to study differentiation, activation and localization of murine macrophages.
Binding of microorganisms to the macrophage plasma membrane: effect of enzymes and periodate. Binding of Neisseria gonorrhoeae by lectin-like receptors on human phagocytes. The influence of chemotactic factors on the expression of phagocyte receptors.
Membrane changes in murine macrophages after in vivo stimulation and activation. Impaired bacterial binding to peritoneal exudate cells from mice with alloxan induced diabetes. Enhanced susceptibility of mice with streptozotocin-induced diabetes to type III Group B streptococcal infection.
Macrophage binding of Staphylococcus albus is blocked by anti-I region alloantibody. Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide. Characterization of patients with an increased susceptibility to bacterial infections and a genetic deficiency of leucocyte membrane complement receptor type 3 and the related membrane antigen LFA A novel macrophage receptor for glucose-modified proteins is distinct from previously described scavenger receptors.
Non enzymatic glycosylation and the pathogenesis of diabetic complications. Suggestive evidence that the mouse macrophage surface receptor for macrophage activating factor MAF may be a glycoprotein containing D-mannose and sialic acid as essential components. Demonstration of a lymphocyte cell-surface mannosephosphate binding activity and correlation with recirculation potential.
Lymphocyte homing receptor: relationship between the mel antigen and a cell-surface antigen. Involvement of sialic acid on endothelial cells in organ-specific lymphocyte recirculation.
Blood groups and Forssman antigenic determinants shared between microbes and mammalian cells. In these tissues it was specifically located at the places of the junctional complexes. We have thus demonstrated that adhesion of adult rat hepatocytes is characterized by specificity both at the molecular and the cellular levels. However, the specificity at the cellular level was not complete, since the same cell-cell adhesion molecule was also present in some simple epithelia in addition to the liver.
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